Development

From Analytical Pipelines to custom sequence and HMM databases, I can help you get the most out of your data. From the simplest install to the most difficult algorithm development, drop me a line and let's talk.

 

 

Testing

What are the limitations of your product?
What makes it better than the rest?

I can analyze the strong and weak points in your bioinformatics software, pushing it to the wall and seeing where it fails. Your development team may not like it at first, but the end result is a more stable product, good ideas about new directions, and a strong impression of product marketability.

How does it compare to the competition? Don't wait for bad news to surprise you in the months and years ahead. Red ink is not your color. I can make a frank, fresh appraisal that can make all the difference in the world.

And, through this process we find valuable information for the marketing department. Wouldn’t they just love to find some concrete examples where you blow away the competition?

Contact me at: MartinGollery@hotmail.com

 

 

Hidden Markov Models

Are you working with genomic or amino data that is difficult to characterize, or would you simply like the best analysis possible using state-of –the-art protein modeling? Rather than trust your analyses to a standard scoring matrix, build a position specific scoring matrix, or better yet, a hidden Markov model (HMM) to represent the full range of variation in your protein family of interest. For more information, see the Handbook of Hidden Markov Models in Bioinformatics, available now on Amazon and most other science bookstores.

 

The TLFAMs databases are a set of protein family HMM databases that are specific to certain classes of organisms. This method has been shown to provide excellent results when analyzing new genomes.

I am the author of the TLFAMs databases, as well as many others that are available at www.hiddenmarkovmodels.com and the primary author of the TLFAM paper in the ‘Omics’ journal. I can show you how these models will drastically improve your annotation. Don't get stuck in the same old BLAST rut- there is more to Bioinformatics than that!

Custom protein modeling can also be done. Contact me at: MartinGollery@hotmail.com